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Отсюда и название: болезнь сочетает анемию (недостаточное число эритроцитов, низкий уровень гемоглобина) и аплазию кроветворения (угнетение выработки всех клеток крови) [2](https://podari-zhizn.ru/ru/get-help/meditsinskii-spravochnik/spravochnik-po-boleznyam/aplasticheskaya-anemiya). \n\n**Распространённость**: около 2–3 случаев на миллион человек в год [3](https://ProBolezny.ru/aplasticheskaya-anemiya/). Может поражать людей любого возраста, но пики заболеваемости наблюдаются у молодых взрослых (в 15–25 лет) и пожилых пациентов (старше 60 лет) [3](https://ProBolezny.ru/aplasticheskaya-anemiya/).\n\n## Причины\nАпластическая анемия может проявляться в двух формах [3](https://ProBolezny.ru/aplasticheskaya-anemiya/): \n1. **Врождённая** — развивается в результате генетических мутаций, которые приводят к дефектам костного мозга и нарушению выработки кровяных клеток [3](https://ProBolezny.ru/aplasticheskaya-anemiya/). \n2. **Приобретённая** — развивается под воздействием внешних факторов [3](https://ProBolezny.ru/aplasticheskaya-anemiya/). Некоторые из них: \n * лекарства (некоторые антибиотики, нестероидные противовоспалительные препараты, антиконвульсанты и химиотерапевтические препараты) [3](https://ProBolezny.ru/aplasticheskaya-anemiya/); \n * химические вещества (длительное воздействие токсичных химикатов, таких как бензол, его производные и пестициды) [3](https://ProBolezny.ru/aplasticheskaya-anemiya/); \n * высокие дозы радиации [3](https://ProBolezny.ru/aplasticheskaya-anemiya/); \n * вирусные инфекции (вирус Эпштейна — Барр, парвовирус B19, гепатит и ВИЧ) [3](https://ProBolezny.ru/aplasticheskaya-anemiya/). \n\nВ большинстве случаев причина заболевания неизвестна — в этом случае говорят об идиопатической апластической анемии [2](https://podari-zhizn.ru/ru/get-help/meditsinskii-spravochnik/spravochnik-po-boleznyam/aplasticheskaya-anemiya)[8](https://unclinic.ru/aplasticheskaja-anemija-prichiny-metody-diagnostiki-i-lechenija/).\n\n## Симптомы\nПроявления апластической анемии связаны с дефицитом всех видов клеток крови [2](https://podari-zhizn.ru/ru/get-help/meditsinskii-spravochnik/spravochnik-po-boleznyam/aplasticheskaya-anemiya): \n* **Недостаток эритроцитов** — бледность, слабость, одышка, учащённое сердцебиение, головокружения, головные боли [2](https://podari-zhizn.ru/ru/get-help/meditsinskii-spravochnik/spravochnik-po-boleznyam/aplasticheskaya-anemiya). \n* **Недостаток тромбоцитов** — кровотечения, в том числе из носа и дёсен, появление синяков и петехий (мелких подкожных кровоизлияний) [2](https://podari-zhizn.ru/ru/get-help/meditsinskii-spravochnik/spravochnik-po-boleznyam/aplasticheskaya-anemiya). \n* **Недостаток лейкоцитов** — слабая сопротивляемость инфекциям, могут возникнуть инфекционные заболевания, плохо поддающиеся терапии или часто повторяющиеся [2](https://podari-zhizn.ru/ru/get-help/meditsinskii-spravochnik/spravochnik-po-boleznyam/aplasticheskaya-anemiya).\n\n## Диагностика\nПри подозрении на апластическую анемию следует обратиться к гематологу — специалисту по заболеваниям крови [3](https://ProBolezny.ru/aplasticheskaya-anemiya/). Некоторые методы диагностики: \n* **Общий анализ крови** — показывает снижение количества форменных элементов крови [1](https://zoon.ru/article/med/aplasticheskaja-anemija/). \n* **Пункция костного мозга** — анализ, осуществляемый путём прокола костной пластинки, необходим для оценки функциональности и строения стволовых клеток [1](https://zoon.ru/article/med/aplasticheskaja-anemija/).\n\n## Лечение\nЛечение тяжёлой и сверхтяжёлой апластической анемии должно быть начато сразу после постановки диагноза, так как состояние серьёзного дефицита всех клеток крови опасно для жизни [2](https://podari-zhizn.ru/ru/get-help/meditsinskii-spravochnik/spravochnik-po-boleznyam/aplasticheskaya-anemiya). Некоторые методы терапии: \n* **Иммуносупрессивная терапия** — направлена на подавление иммунной системы, «атакующей» клетки костного мозга [2](https://podari-zhizn.ru/ru/get-help/meditsinskii-spravochnik/spravochnik-po-boleznyam/aplasticheskaya-anemiya). \n* **Терапия гемокомпонентами** — может включать переливание красных клеток крови для повышения уровня гемоглобина и тромбоцитов для устранения проблем с кровообращением и предотвращения кровотечений [13](https://www.labquest.ru/pyatigorsk/articles/aplasticheskaya-anemiya/). \n* **При самых тяжёлых формах** — трансплантация костного мозга (или стволовых клеток) [13](https://www.labquest.ru/pyatigorsk/articles/aplasticheskaya-anemiya/).","linksData":[{"sourceId":1,"url":"https://zoon.ru/article/med/aplasticheskaja-anemija/","shownUrl":"https://zoon.ru/article/med/aplasticheskaja-anemija/","title":"Апластическая анемия – что это за болезнь, 💉 лечение, симптомы и 🔬 диагностика на МЕД Zoon","shortUrl":"zoon.ru","isTranslated":false,"description":"","greenUrl":"zoon.ru"},{"sourceId":2,"url":"https://podari-zhizn.ru/ru/get-help/meditsinskii-spravochnik/spravochnik-po-boleznyam/aplasticheskaya-anemiya","shownUrl":"https://podari-zhizn.ru/ru/get-help/meditsinskii-spravochnik/spravochnik-po-boleznyam/aplasticheskaya-anemiya","title":"Апластическая анемия — причины, признаки и симптомы, диагностика и лечение","shortUrl":"podari-zhizn.ru","isTranslated":false,"description":"","greenUrl":"podari-zhizn.ru"},{"sourceId":3,"url":"https://ProBolezny.ru/aplasticheskaya-anemiya/","shownUrl":"https://ProBolezny.ru/aplasticheskaya-anemiya/","title":"Апластическая анемия: причины, симптомы и лечение в статье гематолога Сидорова Н. 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