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Со временем суставы срастаются (анкилоз), что приводит к потере подвижности позвоночника [1](https://volgograd.sovamed.ru/zabolevaniya/ankiloziruyushchiy-spondilit/)[4](https://smartclinicspb.ru/zabolevaniy/bolezn-behtereva-ankiloziruyushchiy-spondiloartrit/). \n\nЗаболевание чаще диагностируют у мужчин, чем у женщин, высокий риск заболеваемости — у молодых пациентов (25–40 лет) [1](https://volgograd.sovamed.ru/zabolevaniya/ankiloziruyushchiy-spondilit/).\n\n\n\n## Причины\nТочные причины болезни Бехтерева неизвестны [4](https://smartclinicspb.ru/zabolevaniy/bolezn-behtereva-ankiloziruyushchiy-spondiloartrit/). Некоторые факторы, которые могут способствовать развитию заболевания: \n* **Наследственная предрасположенность** — наличие гена HLA-B27, который повышает риск развития болезни [4](https://smartclinicspb.ru/zabolevaniy/bolezn-behtereva-ankiloziruyushchiy-spondiloartrit/)[8](https://www.smclinic-spb.ru/zabolevaniya/bolezn-bekhtereva). \n* **Изменения иммунного статуса** — могут возникать на фоне острых или хронических инфекционных процессов, переохлаждений [6](https://www.altermed.ru/orthopedics-vertebrology/ankylosing-spondylitis/). \n* **Травмы** — ушибы и повреждения позвоночника и костей таза [6](https://www.altermed.ru/orthopedics-vertebrology/ankylosing-spondylitis/).\n\n## Симптомы\nНекоторые симптомы болезни Бехтерева: \n* **Боль в позвоночнике** — ослабевает при активных движениях и возрастает во время длительного периода малой подвижности (например, ночью) [3](https://www.OnClinic.ru/spondiloartrity/). \n* **Скованность движений** — чаще по утрам [3](https://www.OnClinic.ru/spondiloartrity/). \n* **Иногда боли, небольшой отёк и ограниченность движений** возникают в суставах конечностей (плечевом, тазобедренном, суставах кистей и стоп, височно-нижнечелюстном) [3](https://www.OnClinic.ru/spondiloartrity/). \n* **При длительном развитии** ограничения подвижности становятся постоянными [3](https://www.OnClinic.ru/spondiloartrity/).\n\n## Диагностика\nДиагноз ставится на основании комплексного обследования пациента [11](https://citilab.ru/articles/o-bolezni-bekhtereva-ankiloziruyushchem-spondiloartrite/). Некоторые методы диагностики: \n* **Осмотр** — врач оценивает форму позвоночника, положение туловища, головы, верхних и нижних конечностей [11](https://citilab.ru/articles/o-bolezni-bekhtereva-ankiloziruyushchem-spondiloartrite/). \n* **Лабораторные исследования** — общий анализ крови (определение СОЭ), биохимический анализ крови (определение С-реактивного белка) [11](https://citilab.ru/articles/o-bolezni-bekhtereva-ankiloziruyushchem-spondiloartrite/). \n* **Инструментальные методы** — рентгенологическое исследование, магнитно-резонансная томография (МРТ) [11](https://citilab.ru/articles/o-bolezni-bekhtereva-ankiloziruyushchem-spondiloartrite/).\n\n## Лечение\n**Полностью вылечить болезнь Бехтерева невозможно** [13](https://gemotest.ru/info/spravochnik/zabolevaniya/bolezn-bekhtereva-ankiloziruyushchiy-spondiloartrit/). Лечение направлено на уменьшение боли и воспаления, поддержание подвижности и предотвращение осложнений [4](https://smartclinicspb.ru/zabolevaniy/bolezn-behtereva-ankiloziruyushchiy-spondiloartrit/). Некоторые методы терапии: \n* **Медикаментозная терапия** — нестероидные противовоспалительные препараты, базисные противовоспалительные препараты, генно-инженерные биологические препараты [4](https://smartclinicspb.ru/zabolevaniy/bolezn-behtereva-ankiloziruyushchiy-spondiloartrit/)[13](https://gemotest.ru/info/spravochnik/zabolevaniya/bolezn-bekhtereva-ankiloziruyushchiy-spondiloartrit/). \n* **Лечебная физкультура** — помогает снять боль в суставах и поддерживать подвижность позвоночника [13](https://gemotest.ru/info/spravochnik/zabolevaniya/bolezn-bekhtereva-ankiloziruyushchiy-spondiloartrit/). \n* **Массаж** — позволяет улучшить приток крови к поражённым суставам и обеспечить их питательными веществами [13](https://gemotest.ru/info/spravochnik/zabolevaniya/bolezn-bekhtereva-ankiloziruyushchiy-spondiloartrit/). \n* **Хирургическое лечение** — если медикаментозная терапия и другие методы лечения не дали результата и болезнь продолжает прогрессировать 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