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Это приводит к утолщению и уплотнению лёгочной ткани, что затрудняет газообмен (обмен кислорода и углекислого газа) [1](https://doct.ru/articles/fibroziruyushhij-alveolit.html). Фиброз уменьшает эластичность дыхательных органов, что снижает их функциональную способность [1](https://doct.ru/articles/fibroziruyushhij-alveolit.html). \n\nЗаболевание обычно развивается у людей старше 50 лет [1](https://doct.ru/articles/fibroziruyushhij-alveolit.html)[3](https://www.invitro.ru/library/bolezni/33112/).\n\n\n\n## Причины\nТочные причины фиброзирующего альвеолита не установлены [3](https://www.invitro.ru/library/bolezni/33112/)[7](https://gemotest.ru/info/spravochnik/zabolevaniya/idiopaticheskiy-lyegochnyy-fibroz-alveolit-lyegkikh/). Некоторые факторы, которые могут усугубить течение заболевания: \n* курение [3](https://www.invitro.ru/library/bolezni/33112/); \n* ингаляционное воздействие неорганической и органической пыли [3](https://www.invitro.ru/library/bolezni/33112/); \n* вирусные инфекции (вирус Эпштейна-Барра, цитомегаловирусы, вирусы гепатита С, герпес-вирусы и др.) [3](https://www.invitro.ru/library/bolezni/33112/); \n* сахарный диабет 2 типа [3](https://www.invitro.ru/library/bolezni/33112/); \n* гастроэзофагеальный рефлюкс [3](https://www.invitro.ru/library/bolezni/33112/); \n* генетические мутации [3](https://www.invitro.ru/library/bolezni/33112/).\n\n## Симптомы\nНекоторые симптомы фиброзирующего альвеолита: \n* одышка — сначала во время физических нагрузок, а затем и в покое [3](https://www.invitro.ru/library/bolezni/33112/); \n* малопродуктивный кашель, при тяжёлом течении — кашель с гнойной мокротой [3](https://www.invitro.ru/library/bolezni/33112/); \n* общая слабость [3](https://www.invitro.ru/library/bolezni/33112/); \n* изменение ногтевых фаланг по типу «барабанных палочек» или «часовых стёкол» [3](https://www.invitro.ru/library/bolezni/33112/); \n* снижение массы тела [3](https://www.invitro.ru/library/bolezni/33112/). \n\nПо мере прогрессирования заболевания появляются признаки дыхательной недостаточности: набухают шейные вены, усиливаются отёки, кожа становится серого цвета [3](https://www.invitro.ru/library/bolezni/33112/).\n\n## Диагностика\nОсновной метод диагностики — **компьютерная томография (КТ)**, которая позволяет оценить состояние лёгких и выявить характерные признаки заболевания [3](https://www.invitro.ru/library/bolezni/33112/). О наличии фиброзирующего альвеолита говорит симптом «матового стекла» — гомогенного затемнения лёгочных полей [3](https://www.invitro.ru/library/bolezni/33112/). \n\nТакже проводят: \n* **Рентгенографию лёгких** — показывает неспецифические изменения, как правило, требует уточнения с помощью КТ [3](https://www.invitro.ru/library/bolezni/33112/). \n* **Спирографию** — показывает нарушение вентиляционной функции лёгких [3](https://www.invitro.ru/library/bolezni/33112/). \n* **Бронхоскопию** — полезна для дифференциальной диагностики с воспалительными или опухолевыми процессами в лёгких [3](https://www.invitro.ru/library/bolezni/33112/). \n* **Биопсию лёгких** — выполняют строго по показаниям [3](https://www.invitro.ru/library/bolezni/33112/).\n\n## Лечение\n**Эффективных препаратов, способных вызвать регресс фиброза, не существует** [3](https://www.invitro.ru/library/bolezni/33112/). Цель терапии — улучшение или стабилизация функциональных нарушений и предотвращение дальнейшего прогрессирования патологии [3](https://www.invitro.ru/library/bolezni/33112/). \n\nТерапия включает противовоспалительные и антифиброзные препараты, иммунодепрессанты, а также их комбинацию [3](https://www.invitro.ru/library/bolezni/33112/). При присоединении вторичной инфекции подбирают антибиотики, противогрибковые средства и увеличивают дозы базовых препаратов [3](https://www.invitro.ru/library/bolezni/33112/). \n\nПри неэффективности терапии может быть рекомендована **трансплантация лёгких** [3](https://www.invitro.ru/library/bolezni/33112/).","linksData":[{"sourceId":1,"url":"https://doct.ru/articles/fibroziruyushhij-alveolit.html","shownUrl":"https://doct.ru/articles/fibroziruyushhij-alveolit.html","title":"Фиброзирующий альвеолит: симптомы, диагностика и лечение","shortUrl":"doct.ru","isTranslated":false,"description":"","greenUrl":"doct.ru"},{"sourceId":2,"url":"https://semeynaya.ru/directions/pulmonologiya/fibroziruyuschiy-alveolit/","shownUrl":"https://semeynaya.ru/directions/pulmonologiya/fibroziruyuschiy-alveolit/","title":"Фиброзирующий альвеолит","shortUrl":"semeynaya.ru","isTranslated":false,"description":"","greenUrl":"semeynaya.ru"},{"sourceId":3,"url":"https://www.invitro.ru/library/bolezni/33112/","shownUrl":"https://www.invitro.ru/library/bolezni/33112/","title":"Фиброзирующий альвеолит - причины появления, симптомы заболевания, диагностика и способы лечения","shortUrl":"invitro.ru","isTranslated":false,"description":"","greenUrl":"invitro.ru"},{"sourceId":4,"url":"https://medcentr-Sochi.ru/terapevt/fibroziruyushchij-alveolit.html","shownUrl":"https://medcentr-Sochi.ru/terapevt/fibroziruyushchij-alveolit.html","title":"Фиброзирующий альвеолит: что это такое, симптомы, причины и лечение у врача терапевта в МКЦ «Проксима» (г. 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