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Чаще всего развивается в органах пищеварительной и дыхательной системы, реже — в лёгких, поджелудочной железе, жёлчном пузыре, вилочковой железе или урогенитальном тракте [5](https://www.KrasotaiMedicina.ru/diseases/oncologic/carcinoid). \n\n**Особенность**: опухоль способна вырабатывать биологически активные вещества — серотонин, гистамин и другие, что усиливает клинические проявления [2](https://www.smclinic.ru/diseases/neyroendokrinnye-opukholi-kartsinoid/).\n\n\n\n## Причины\nТочная причина формирования карциноида пока остаётся не до конца выясненной [2](https://www.smclinic.ru/diseases/neyroendokrinnye-opukholi-kartsinoid/). Учёные предполагают, что к возникновению заболевания приводит комплекс факторов [2](https://www.smclinic.ru/diseases/neyroendokrinnye-opukholi-kartsinoid/): \n* наследственная предрасположенность и генетические мутации [2](https://www.smclinic.ru/diseases/neyroendokrinnye-opukholi-kartsinoid/); \n* хронические воспалительные процессы в области желудочно-кишечного тракта [2](https://www.smclinic.ru/diseases/neyroendokrinnye-opukholi-kartsinoid/); \n* гормональные сбои и нарушения эндокринной регуляции [2](https://www.smclinic.ru/diseases/neyroendokrinnye-opukholi-kartsinoid/); \n* воздействие канцерогенов, химических веществ и радиации [2](https://www.smclinic.ru/diseases/neyroendokrinnye-opukholi-kartsinoid/); \n* аутоиммунные процессы и снижение контроля иммунной системы [2](https://www.smclinic.ru/diseases/neyroendokrinnye-opukholi-kartsinoid/).\n\n## Симптомы\nПроявления карциноидных опухолей зависят от их локализации, активности, степени дифференцировки и стадии заболевания [2](https://www.smclinic.ru/diseases/neyroendokrinnye-opukholi-kartsinoid/). Некоторые симптомы: \n* при карциноидных опухолях кишечника — боли в животе, диарея, вздутие [2](https://www.smclinic.ru/diseases/neyroendokrinnye-opukholi-kartsinoid/); \n* у пациентов с нейроэндокринной опухолью поджелудочной железы — гипогликемия, язвы, резкие скачки сахара [2](https://www.smclinic.ru/diseases/neyroendokrinnye-opukholi-kartsinoid/); \n* карциноидный синдром: покраснение лица, бронхоспазм, тахикардия [2](https://www.smclinic.ru/diseases/neyroendokrinnye-opukholi-kartsinoid/); \n* снижение массы тела, утомляемость, слабость [2](https://www.smclinic.ru/diseases/neyroendokrinnye-opukholi-kartsinoid/). \n\nВ запущенных случаях могут развиваться кровотечения, кишечная непроходимость или ателектаз лёгкого [5](https://www.KrasotaiMedicina.ru/diseases/oncologic/carcinoid).\n\n## Диагностика\nДля диагностики карциноидных опухолей используют, например: \n* **Лабораторные анализы** — биохимические маркеры показывают степень развития новообразования и его активность [11](https://hadassah.moscow/onkologia/karczinoidnaya-opuhol/). \n* **Визуализирующие методы** — гастроскопия и колоноскопия для выявления опухолей желудка, двенадцатиперстной кишки, толстой кишки, капсульная эндоскопия — при подозрении на опухоль тонкой кишки [11](https://hadassah.moscow/onkologia/karczinoidnaya-opuhol/). \n* **КТ с контрастом** — выявляет первичную опухоль и метастазы (особенно в печень) [11](https://hadassah.moscow/onkologia/karczinoidnaya-opuhol/). \n* **МРТ** — лучше визуализирует метастазы в печень и мягкие ткани, используется при подозрении на опухоли поджелудочной железы [11](https://hadassah.moscow/onkologia/karczinoidnaya-opuhol/). \n* **Биопсия** — позволяет точно подтвердить природу опухоли, определить её тип и степень злокачественности [11](https://hadassah.moscow/onkologia/karczinoidnaya-opuhol/).\n\n## Лечение\nТактика лечения подбирается индивидуально, исходя из местоположения, стадии развития болезни, гормональной активности и степени злокачественности [11](https://hadassah.moscow/onkologia/karczinoidnaya-opuhol/). Некоторые методы: \n* **Хирургическое лечение** — основной метод для локализованных опухолей [11](https://hadassah.moscow/onkologia/karczinoidnaya-opuhol/). Удаляться может как вся опухоль полностью, так и часть опухоли для уменьшения симптомов при метастазах [11](https://hadassah.moscow/onkologia/karczinoidnaya-opuhol/). \n* **Гормональная терапия** — необходима при гормонально активных формах, замедляет рост новообразования и предотвращает метастазы [11](https://hadassah.moscow/onkologia/karczinoidnaya-opuhol/). \n* **Химиотерапия** — применяется при быстром прогрессировании опухоли и наличии метастазов [11](https://hadassah.moscow/onkologia/karczinoidnaya-opuhol/). \n* **Лучевая терапия** — используется ограниченно из-за низкой чувствительности карциноидной опухоли к ионизирующему излучению [11](https://hadassah.moscow/onkologia/karczinoidnaya-opuhol/). 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