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Обычно подагра поражает сустав большого пальца ноги, но может затронуть и лодыжку, колено, локоть, запястье или палец руки [5](https://gemotest.ru/info/spravochnik/zabolevaniya/podagra/). \n\n**Лечением** заболевания занимаются ревматологи, артрологи и нефрологи [3](https://www.smclinic.ru/diseases/podagra/)[7](https://lit-clinic.ru/diseases/podagra/).\n\n\n\n## Причины\nОсновной фактор — **гиперурикемия** — увеличение концентрации мочевой кислоты в крови [7](https://lit-clinic.ru/diseases/podagra/). В обычных условиях её избыток удаляется через почки, но при снижении их функциональности, генетической предрасположенности, избыточной массе тела или чрезмерном употреблении пуриносодержащих продуктов (в частности, мяса и алкоголя) процесс выведения нарушается [7](https://lit-clinic.ru/diseases/podagra/). В результате вещество накапливается, формируя кристаллы, которые встраиваются в суставные структуры и провоцируют воспалительные реакции [7](https://lit-clinic.ru/diseases/podagra/).\n\n## Симптомы\n**Острый приступ** — сильная, внезапная боль в суставе, чаще всего локализованная в районе большого пальца ноги [7](https://lit-clinic.ru/diseases/podagra/). Участок воспаления становится ярко-красным, отекает, кожа над ним ощущается горячей на ощупь, а движения в поражённой зоне значительно затруднены [7](https://lit-clinic.ru/diseases/podagra/). Продолжительность приступа — от нескольких часов до нескольких суток [7](https://lit-clinic.ru/diseases/podagra/). \n\n**Хроническая подагра** — если не лечить болезнь, со временем развивается хроническое течение с частыми рецидивами [7](https://lit-clinic.ru/diseases/podagra/). Поражаются различные суставы, образуются тофусы — плотные подкожные образования, содержащие кристаллы уратов [7](https://lit-clinic.ru/diseases/podagra/). Суставы деформируются, нарушается их функция, а также развиваются осложнения со стороны почек, включая мочекаменную болезнь и почечную недостаточность [7](https://lit-clinic.ru/diseases/podagra/).\n\n## Диагностика\n**Для точной диагностики подагры необходимо комплексное обследование** [7](https://lit-clinic.ru/diseases/podagra/). Некоторые методы: \n* **Анализ крови** — позволяет выявить повышение уровня мочевой кислоты [7](https://lit-clinic.ru/diseases/podagra/). \n* **Рентгенография суставов** — на поздних стадиях выявляет изменения костей и признаки отложения кристаллов [7](https://lit-clinic.ru/diseases/podagra/). \n* **Пункция сустава** — даёт возможность исследовать суставную жидкость, обнаружение уратов — точное подтверждение диагноза [7](https://lit-clinic.ru/diseases/podagra/). \n* **УЗИ почек** — для оценки состояния почек и выявления осложнений (например, камней) [7](https://lit-clinic.ru/diseases/podagra/).\n\n## Лечение\n**Цель терапии** — уменьшение уровня мочевой кислоты, купирование болевых симптомов, предотвращение рецидивов и осложнений [7](https://lit-clinic.ru/diseases/podagra/). 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