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Это редкий, но крайне агрессивный вид злокачественных новообразований [2](https://doct.ru/diseases/rak-zhelchnogo-puzyrya.html)[4](https://www.oncology-centr.ru/diseases/onkologicheskie-zabolevaniya-organov-zhkt/rak-zhelchnogo-puzyrya/). \n\n**Опасность** — скрытое течение: клинические проявления долгое время отсутствуют, что приводит к поздней диагностике [2](https://doct.ru/diseases/rak-zhelchnogo-puzyrya.html). Опухоль может вовлекать в патологический процесс печень, жёлчные протоки, двенадцатиперстную кишку и даже поджелудочную железу [2](https://doct.ru/diseases/rak-zhelchnogo-puzyrya.html).\n\n\n\n## Причины\nТочные механизмы, запускающие процесс злокачественного перерождения клеток слизистой желчного пузыря, до конца не выяснены [2](https://doct.ru/diseases/rak-zhelchnogo-puzyrya.html). Однако выделяют ряд факторов, повышающих риск развития этой патологии [2](https://doct.ru/diseases/rak-zhelchnogo-puzyrya.html): \n* **Хронический холецистит** — длительное воспаление провоцирует изменения слизистой оболочки [4](https://www.oncology-centr.ru/diseases/onkologicheskie-zabolevaniya-organov-zhkt/rak-zhelchnogo-puzyrya/). \n* **Желчнокаменная болезнь** — постоянная травматизация стенок пузыря камнями [4](https://www.oncology-centr.ru/diseases/onkologicheskie-zabolevaniya-organov-zhkt/rak-zhelchnogo-puzyrya/). \n* **Наследственная предрасположенность** — если у ближайших родственников диагностировались злокачественные опухоли ЖКТ, риск возрастает [4](https://www.oncology-centr.ru/diseases/onkologicheskie-zabolevaniya-organov-zhkt/rak-zhelchnogo-puzyrya/). \n* **Нарушения обмена веществ**, в частности ожирение и сахарный диабет [4](https://www.oncology-centr.ru/diseases/onkologicheskie-zabolevaniya-organov-zhkt/rak-zhelchnogo-puzyrya/). \n* **Неправильное питание и малоподвижный образ жизни**, способствующие застою желчи [4](https://www.oncology-centr.ru/diseases/onkologicheskie-zabolevaniya-organov-zhkt/rak-zhelchnogo-puzyrya/).\n\n## Симптомы\n**На ранних стадиях** симптомы отсутствуют либо имитируют проявления хронического холецистита [7](https://inuclear.ru/zabolevanija/rak-zhelchnogo-puzyrya/). **По мере роста опухоли** появляются тупая боль или дискомфорт в правом подреберье, тяжесть после еды, тошнота, потеря аппетита [7](https://inuclear.ru/zabolevanija/rak-zhelchnogo-puzyrya/). \n\n**Часто развивается желтуха** из-за сдавления жёлчных протоков, а также потемнение мочи и обесцвечивание кала [7](https://inuclear.ru/zabolevanija/rak-zhelchnogo-puzyrya/). Возможны лихорадка, похудение, слабость, а при распространении — асцит и отёки [7](https://inuclear.ru/zabolevanija/rak-zhelchnogo-puzyrya/).\n\n## Диагностика\n**Для диагностики рака желчного пузыря используют**: \n* **УЗИ органов брюшной полости** — позволяет обнаружить опухоль, её локализацию, распространение на другие ткани и органы [12](https://www.smclinic.ru/diseases/rak-zhelchnogo-puzyrya/)[15](https://cpm-devita.ru/onko/onkologiya-zhkt/rak-zhelchnogo-puzyrya/). \n* **Компьютерную томографию (КТ) и магнитно-резонансную томографию (МРТ)** — помогают оценить местное распространение и состояние печени, лимфоузлов и сосудов [7](https://inuclear.ru/zabolevanija/rak-zhelchnogo-puzyrya/)[15](https://cpm-devita.ru/onko/onkologiya-zhkt/rak-zhelchnogo-puzyrya/). \n* **Биопсию** — забор образцов ткани для микроскопического исследования [13](https://lapino2.ru/napravleniya/torakoabdominalnaya-onkologiya/rak-zhelchnogo-puzyrya/)[14](https://oncology-spb.ru/zabolevaniya/organy-zhkt/rak-zhelchnogo-puzyrya).\n\n## Лечение\n**Тактика лечения** зависит от стадии заболевания, степени прорастания опухоли в соседние органы и крупные сосуды, общего состояния пациента [15](https://cpm-devita.ru/onko/onkologiya-zhkt/rak-zhelchnogo-puzyrya/). **Некоторые методы**: \n* **Хирургическое удаление желчного пузыря (холецистэктомия)** — показано, если опухоль проросла в стенку органа дальше мышечного слоя, при этом метастазирования ещё нет [16](https://teledoctor24.ru/article/824-1-rak-zhelchnogo-puzyrya/). \n* **Химиотерапия** — назначается после операции или в случаях, когда оперативное вмешательство невозможно [16](https://teledoctor24.ru/article/824-1-rak-zhelchnogo-puzyrya/). \n* **Лучевая терапия** — проводится вместе с химиотерапией, назначается также при неоперабельном раке или после хирургического удаления опухоли [16](https://teledoctor24.ru/article/824-1-rak-zhelchnogo-puzyrya/). \n\n**Ранняя диагностика и своевременное лечение** значительно улучшают прогноз, хотя в целом он остаётся неблагоприятным из-за позднего выявления [7](https://inuclear.ru/zabolevanija/rak-zhelchnogo-puzyrya/).","linksData":[{"sourceId":1,"url":"https://semeynaya.ru/directions/onkologiya/rak-zhelchnogo-puzyrya/","shownUrl":"https://semeynaya.ru/directions/onkologiya/rak-zhelchnogo-puzyrya/","title":"Рак желчного пузыря","shortUrl":"semeynaya.ru","isTranslated":false,"description":"","greenUrl":"semeynaya.ru"},{"sourceId":2,"url":"https://doct.ru/diseases/rak-zhelchnogo-puzyrya.html","shownUrl":"https://doct.ru/diseases/rak-zhelchnogo-puzyrya.html","title":"Рак желчного пузыря (РЖП) - 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