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Обычно клетки содержат две копии каждой хромосомы, но при синдроме Дауна появляется третья копия 21-й хромосомы [1](https://Megapteka.ru/specials/sindrom-dauna-626). Это влияет на развитие организма, вызывая характерные физические признаки и когнитивные нарушения различной степени выраженности [1](https://Megapteka.ru/specials/sindrom-dauna-626).\n\n\n\n## Причины\nПоявление дополнительной хромосомы может быть обусловлено [7](https://yandex.ru/medicine/disease/sindrom-dauna): \n* **Генетической случайностью** (нерасхождением парных хромосом в овогенезе или сперматогенезе) [7](https://yandex.ru/medicine/disease/sindrom-dauna). \n* **Нарушением клеточного деления** после оплодотворения яйцеклетки и развития плода [6](https://neurospectrum.ru/zabolevaniya/sindrom-dauna-prichiny-vozniknoveniya-u-detey/)[7](https://yandex.ru/medicine/disease/sindrom-dauna). \n* **Наследованием генетической мутации** от матери или отца [7](https://yandex.ru/medicine/disease/sindrom-dauna). \n\nСиндром Дауна не является наследственным заболеванием, хотя предрасположенность к его развитию существует [3](https://helix.ru/kb/item/726).\n\n## Симптомы\nНекоторые признаки синдрома Дауна: \n* **Черты лица**: круглое лицо, плоский профиль носа, приподнятые уголки глаз («монголоидный разрез») [1](https://Megapteka.ru/specials/sindrom-dauna-626). \n* **Физические характеристики**: низкая мышечная масса тела, короткие конечности, большой язык, складка кожи над внутренними углами глаз [1](https://Megapteka.ru/specials/sindrom-dauna-626). \n* **Особенности здоровья**: склонность к заболеваниям сердца, слуховым проблемам, ослаблению иммунитета [1](https://Megapteka.ru/specials/sindrom-dauna-626). \n* **Психоэмоциональные аспекты**: замедленное психическое развитие, трудности с концентрацией внимания, обучение требует большего времени и терпения [1](https://Megapteka.ru/specials/sindrom-dauna-626).\n\n## Диагностика\nДиагностика синдрома Дауна может быть проведена как до рождения (пренатальная диагностика), так и после рождения (постнатальная диагностика) [13](https://kdl.ru/patient/blog/sindrom-dauna). Некоторые методы: \n* **Пренатальная диагностика**: ультразвуковое исследование плода, биохимический скрининг крови матери, неинвазивный пренатальный скрининг (анализ фрагментов ДНК плода, циркулирующих в крови матери) [13](https://kdl.ru/patient/blog/sindrom-dauna). \n* **Постнатальная диагностика**: физическое обследование, кариотипирование — анализ хромосом из образца крови ребёнка для подтверждения диагноза [13](https://kdl.ru/patient/blog/sindrom-dauna).\n\n## Лечение\n**Лечения синдрома Дауна не существует** [10](https://stolichki.ru/clubs/health/diseases_with_a_name/sindrom-dauna)[15](https://www.KrasotaiMedicina.ru/diseases/children/down-syndrome). Терапия направлена на улучшение качества жизни пациента и коррекцию сопутствующих заболеваний [1](https://Megapteka.ru/specials/sindrom-dauna-626)[15](https://www.KrasotaiMedicina.ru/diseases/children/down-syndrome). Например: \n* При выявлении тяжёлых врождённых пороков сердца и ЖКТ показана их ранняя хирургическая коррекция [15](https://www.KrasotaiMedicina.ru/diseases/children/down-syndrome). \n* Для стимуляции развития моторных навыков показана физиотерапия, занятия ЛФК [15](https://www.KrasotaiMedicina.ru/diseases/children/down-syndrome). \n* Для развития речевых и коммуникативных навыков детям с синдромом Дауна необходимы занятия с логопедом [15](https://www.KrasotaiMedicina.ru/diseases/children/down-syndrome).","linksData":[{"sourceId":1,"url":"https://Megapteka.ru/specials/sindrom-dauna-626","shownUrl":"https://Megapteka.ru/specials/sindrom-dauna-626","title":"Синдром Дауна: Причины, симптомы, диагностика, лечение","shortUrl":"Megapteka.ru","isTranslated":false,"description":"","greenUrl":"Megapteka.ru"},{"sourceId":2,"url":"https://www.invitro.ru/library/bolezni/33546/","shownUrl":"https://www.invitro.ru/library/bolezni/33546/","title":"Синдром Дауна - причины появления, симптомы заболевания, диагностика и способы лечения","shortUrl":"invitro.ru","isTranslated":false,"description":"","greenUrl":"invitro.ru"},{"sourceId":3,"url":"https://helix.ru/kb/item/726","shownUrl":"https://helix.ru/kb/item/726","title":"Синдром Дауна","shortUrl":"helix.ru","isTranslated":false,"description":"","greenUrl":"helix.ru"},{"sourceId":4,"url":"https://www.smdoctor.ru/about/articles/deti-sindrom-dauna/","shownUrl":"https://www.smdoctor.ru/about/articles/deti-sindrom-dauna/","title":"Дети с синдромом Дауна - особенности развития | Статьи «СМ-Клиника» для детей и подростков","shortUrl":"smdoctor.ru","isTranslated":false,"description":"","greenUrl":"smdoctor.ru"},{"sourceId":5,"url":"https://doct.ru/articles/sindrom-dauna.html","shownUrl":"https://doct.ru/articles/sindrom-dauna.html","title":"Синдром Дауна - причины появления, симптомы и прогноз","shortUrl":"doct.ru","isTranslated":false,"description":"","greenUrl":"doct.ru"},{"sourceId":6,"url":"https://neurospectrum.ru/zabolevaniya/sindrom-dauna-prichiny-vozniknoveniya-u-detey/","shownUrl":"https://neurospectrum.ru/zabolevaniya/sindrom-dauna-prichiny-vozniknoveniya-u-detey/","title":"Синдром Дауна: помощь детям – сеть клиник детской неврологии в Москве","shortUrl":"neurospectrum.ru","isTranslated":false,"description":"","greenUrl":"neurospectrum.ru"},{"sourceId":7,"url":"https://yandex.ru/medicine/disease/sindrom-dauna","shownUrl":"https://yandex.ru/medicine/disease/sindrom-dauna","title":"Синдром Дауна - симптомы, причины и лечение","shortUrl":"yandex.ru","isTranslated":false,"description":"","greenUrl":"yandex.ru"},{"sourceId":8,"url":"https://MedPortal.ru/enc/pediatrics/Down/sindrom-dauna/","shownUrl":"https://MedPortal.ru/enc/pediatrics/Down/sindrom-dauna/","title":"Синдром Дауна: риск, причины, признаки при беременности","shortUrl":"MedPortal.ru","isTranslated":false,"description":"","greenUrl":"MedPortal.ru"},{"sourceId":9,"url":"https://www.smclinic.ru/diseases/sindrom-dauna/","shownUrl":"https://www.smclinic.ru/diseases/sindrom-dauna/","title":"Синдром Дауна - симптомы, причины, признаки, степени, виды и лечение в Москве в «СМ-Клиника»","shortUrl":"smclinic.ru","isTranslated":false,"description":"","greenUrl":"smclinic.ru"},{"sourceId":10,"url":"https://stolichki.ru/clubs/health/diseases_with_a_name/sindrom-dauna","shownUrl":"https://stolichki.ru/clubs/health/diseases_with_a_name/sindrom-dauna","title":"Синдром Дауна: причины, симптомы и проявления даунизма","shortUrl":"stolichki.ru","isTranslated":false,"description":"","greenUrl":"stolichki.ru"},{"sourceId":11,"url":"https://deti-indigo74.ru/chto-lechim/s/sindrom-dauna/","shownUrl":"https://deti-indigo74.ru/chto-lechim/s/sindrom-dauna/","title":"Синдром Дауна — Что лечим НИИ «Дети Индиго»","shortUrl":"deti-indigo74.ru","isTranslated":false,"description":"","greenUrl":"deti-indigo74.ru"},{"sourceId":12,"url":"https://www.logopediadoma.ru/sindrom-dauna","shownUrl":"https://www.logopediadoma.ru/sindrom-dauna","title":"Синдром Дауна","shortUrl":"logopediadoma.ru","isTranslated":false,"description":"","greenUrl":"logopediadoma.ru"},{"sourceId":13,"url":"https://kdl.ru/patient/blog/sindrom-dauna","shownUrl":"https://kdl.ru/patient/blog/sindrom-dauna","title":"Синдром Дайуна причины и факторы риска ранняя диагностика","shortUrl":"kdl.ru","isTranslated":false,"description":"","greenUrl":"kdl.ru"},{"sourceId":14,"url":"https://ProBolezny.ru/sindrom-dauna/","shownUrl":"https://ProBolezny.ru/sindrom-dauna/","title":"Синдром Дауна (трисомия 21): причины, симптомы и лечение в статье гинеколога Титоренко А. 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