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[3](https://podari-zhizn.ru/ru/get-help/meditsinskii-spravochnik/spravochnik-po-boleznyam/ostryi-eritroidnyi-leikoz)[5](https://cyberleninka.ru/article/n/ostryy-eritromieloz-razvivshiysya-posle-himioluchevogo-lecheniya-po-povodu-dvuh-solidnyh-opuholey-opisanie-klinicheskogo)[12](https://xn--b1agiaakcdcvfl.xn--p1ai/zabolevaniya/ostryjj-ehritromieloz). \n\nВыделяют две основные формы [12](https://xn--b1agiaakcdcvfl.xn--p1ai/zabolevaniya/ostryjj-ehritromieloz): \n1. **Эритроидная лейкемия** — поражаются преимущественно эритроидные клетки, что приводит к нарушению выработки нормальных эритроцитов [12](https://xn--b1agiaakcdcvfl.xn--p1ai/zabolevaniya/ostryjj-ehritromieloz). \n2. **Эритромиелобластный лейкоз** — сочетает признаки поражения как эритроидных клеток, так и миелоидных, что делает течение заболевания более агрессивным [12](https://xn--b1agiaakcdcvfl.xn--p1ai/zabolevaniya/ostryjj-ehritromieloz).\n\n\n\n## Причины\nТочные причины развития острого эритромиелоза не до конца изучены [12](https://xn--b1agiaakcdcvfl.xn--p1ai/zabolevaniya/ostryjj-ehritromieloz). Однако существуют факторы, повышающие риск заболевания [12](https://xn--b1agiaakcdcvfl.xn--p1ai/zabolevaniya/ostryjj-ehritromieloz): \n* генетические мутации, в том числе хромосомные аномалии [12](https://xn--b1agiaakcdcvfl.xn--p1ai/zabolevaniya/ostryjj-ehritromieloz); \n* воздействие радиации и химических веществ, таких как бензол [12](https://xn--b1agiaakcdcvfl.xn--p1ai/zabolevaniya/ostryjj-ehritromieloz); \n* химиотерапия или лучевая терапия по поводу других злокачественных заболеваний [12](https://xn--b1agiaakcdcvfl.xn--p1ai/zabolevaniya/ostryjj-ehritromieloz); \n* наследственные заболевания, например, синдром Дауна [12](https://xn--b1agiaakcdcvfl.xn--p1ai/zabolevaniya/ostryjj-ehritromieloz); \n* вирусные инфекции, оказывающие влияние на костный мозг [12](https://xn--b1agiaakcdcvfl.xn--p1ai/zabolevaniya/ostryjj-ehritromieloz).\n\n## Симптомы\nНекоторые симптомы острого эритромиелоза: \n* сильная слабость и утомляемость [12](https://xn--b1agiaakcdcvfl.xn--p1ai/zabolevaniya/ostryjj-ehritromieloz); \n* бледность кожи из-за анемии [12](https://xn--b1agiaakcdcvfl.xn--p1ai/zabolevaniya/ostryjj-ehritromieloz); \n* частые инфекционные заболевания вследствие снижения иммунитета [12](https://xn--b1agiaakcdcvfl.xn--p1ai/zabolevaniya/ostryjj-ehritromieloz); \n* кровоточивость дёсен, носовые кровотечения, появление синяков на коже [12](https://xn--b1agiaakcdcvfl.xn--p1ai/zabolevaniya/ostryjj-ehritromieloz); \n* лихорадка, ночная потливость [12](https://xn--b1agiaakcdcvfl.xn--p1ai/zabolevaniya/ostryjj-ehritromieloz); \n* боль в костях и суставах [12](https://xn--b1agiaakcdcvfl.xn--p1ai/zabolevaniya/ostryjj-ehritromieloz); \n* увеличение печени и селезёнки [12](https://xn--b1agiaakcdcvfl.xn--p1ai/zabolevaniya/ostryjj-ehritromieloz).\n\n## Диагностика\nДля диагностики острого эритромиелоза используют следующие методы: \n* **Общий анализ крови** — выявляет анемию, тромбоцитопению и лейкопению [12](https://xn--b1agiaakcdcvfl.xn--p1ai/zabolevaniya/ostryjj-ehritromieloz). \n* **Миелограмма** — исследование костного мозга, которое показывает аномальный рост эритроидных и миелоидных клеток [12](https://xn--b1agiaakcdcvfl.xn--p1ai/zabolevaniya/ostryjj-ehritromieloz). \n* **Цитогенетический анализ** — позволяет выявить хромосомные аномалии, связанные с заболеванием [12](https://xn--b1agiaakcdcvfl.xn--p1ai/zabolevaniya/ostryjj-ehritromieloz). \n* **Иммуногистохимическое исследование** — для определения характера клеток и степени их злокачественности [12](https://xn--b1agiaakcdcvfl.xn--p1ai/zabolevaniya/ostryjj-ehritromieloz). \n* **Молекулярно-генетические тесты** — выявляют мутации, характерные для острого эритромиелоза [12](https://xn--b1agiaakcdcvfl.xn--p1ai/zabolevaniya/ostryjj-ehritromieloz).\n\n## Лечение\nЛечение острого эритромиелоза комплексное и включает [12](https://xn--b1agiaakcdcvfl.xn--p1ai/zabolevaniya/ostryjj-ehritromieloz): \n* **Химиотерапию** — основной метод, направленный на уничтожение злокачественных клеток [12](https://xn--b1agiaakcdcvfl.xn--p1ai/zabolevaniya/ostryjj-ehritromieloz). Применяются комбинации цитостатиков, таких как антрациклины и цитарабин [12](https://xn--b1agiaakcdcvfl.xn--p1ai/zabolevaniya/ostryjj-ehritromieloz). \n* **Пересадку костного мозга** — эффективный метод при рецидивах или тяжёлых формах заболевания, при котором донорские стволовые клетки заменяют поражённые клетки пациента [12](https://xn--b1agiaakcdcvfl.xn--p1ai/zabolevaniya/ostryjj-ehritromieloz). \n* **Таргетную терапию** — использование препаратов, воздействующих на конкретные молекулярные мишени в клетках опухоли [12](https://xn--b1agiaakcdcvfl.xn--p1ai/zabolevaniya/ostryjj-ehritromieloz). \n* **Поддерживающую терапию** — направлена на восстановление уровня эритроцитов, лейкоцитов и тромбоцитов, что снижает риск инфекций и кровотечений [12](https://xn--b1agiaakcdcvfl.xn--p1ai/zabolevaniya/ostryjj-ehritromieloz). \n\nЛечением острого эритромиелоза занимается гематолог — врач, специализирующийся на заболеваниях крови и костного мозга [12](https://xn--b1agiaakcdcvfl.xn--p1ai/zabolevaniya/ostryjj-ehritromieloz).","linksData":[{"sourceId":1,"url":"https://yandex.ru/health/turbo/articles?id=6531","shownUrl":"https://yandex.ru/health/turbo/articles?id=6531","title":"Паллиативная помощь при остром лейкозе","shortUrl":"yandex.ru","isTranslated":false,"description":"","greenUrl":"yandex.ru"},{"sourceId":2,"url":"https://rumedo.ru/uploads/materials/73a912ffb18d7c064b621b039fd30ea6.pdf","shownUrl":"https://rumedo.ru/uploads/materials/73a912ffb18d7c064b621b039fd30ea6.pdf","title":"Современный взгляд на патогенез,","shortUrl":"rumedo.ru","isTranslated":false,"description":"","greenUrl":"rumedo.ru"},{"sourceId":3,"url":"https://podari-zhizn.ru/ru/get-help/meditsinskii-spravochnik/spravochnik-po-boleznyam/ostryi-eritroidnyi-leikoz","shownUrl":"https://podari-zhizn.ru/ru/get-help/meditsinskii-spravochnik/spravochnik-po-boleznyam/ostryi-eritroidnyi-leikoz","title":"Острый эритроидный лейкоз — причины, признаки и симптомы, диагностика и лечение","shortUrl":"podari-zhizn.ru","isTranslated":false,"description":"","greenUrl":"podari-zhizn.ru"},{"sourceId":4,"url":"https://eduherald.ru/article/view?id=20397","shownUrl":"https://eduherald.ru/article/view?id=20397","title":"ЭТИОЛОГИЯ, ПАТОГЕНЕЗ И ДИАГНОСТИКА ОСТРОГО ЭРИТРОЛЕЙКОЗА - 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